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Association between slow-wave sleep and motor progression in Parkinson disease


  • In people with Parkinson disease (PD), higher slow-wave sleep (SWS) was significantly associated with slower motor progression (particularly axial progression) over approximately 5 years compared to those with lower SWS.

Why this matters

  • An interplay between sleep, and particularly deeper sleep, and neurodegeneration in people with PD offers the prospect of a new avenue of treatment.

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