Cerebral microhemorrhage accumulation in heritable Alzheimer’s disease

Takeaway

  • Cerebral microhemorrhages (CMHs) form part of the underlying disease process in dominantly inherited Alzheimer’s disease (DIAD) and are significantly associated with dementia.

Why this matters

  • CMHs are commonly observed in older adults, but it can be difficult to discriminate etiology in this group since they often have mixed pathologies; as such, investigating CMH’s in a younger, at-risk cohort such as those with DIAD, may be useful.

  • The role of CMHs in DIAD may constitute a potentially important imaging marker of disease risk and may influence treatment options for patients as well as their selection in clinical trials for this specific condition; however, further study is warranted for greater clarity.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.