Changes in disability progression in people with multiple sclerosis over time: a Swedish study

Takeaway

  • Risk of reaching Expanded Disability Status Scale (EDSS) scores 3.0, 4.0 and 6.0 has significantly decreased over the last decade in people with relapsing-onset multiple sclerosis (ROMS), but not progressive-onset MS (POMs), in Sweden.

Why this matters

  • The increase in availability of disease modifying therapy (DMT) for treatment of ROMS, but not POMs, could explain the decreased risk of disability progression in ROMs, and highlights a need for improved therapies that target disability outcomes in POMs.

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