Combining genetic and clinical features predicts impulse control disorders in Parkinson’s disease

Takeaway

  • Polymorphisms in the dopa decarboxylase gene could act as biomarkers for increased risk of developing impulse control disorders in Parkinson’s disease.

Why this matters

    This is the first study to link polymorphisms in the dopa decarboxylase gene to impulse control disorders in Parkinson’s disease. This important finding supports the assessment of a person’s genetic background to identify those predisposed to impulse control disorders and to prevent exposure to dopamine agonists that increase risk.