COVID-19 myopathy: specialists show persistence of viral particles in skeletal muscle

Specialists have described a case of COVID-19 myopathy, with electron microscopy (EM) showing persistence of viral particles in the skeletal muscle after repeat coronavirus testing was negative.

Presenting at WMS 2020, Dr Dubravka Dodig from the University of Toronto, Canada, said the case “is the first description of COVID-19 myopathy and EM demonstration of viral particles in the muscle, in keeping with direct infection of the skeletal muscle tissue, to our knowledge.”

Dr Dodig said emerging data suggest that infection with SARS-CoV-2 can trigger autoimmune central and peripheral nervous system manifestations, with muscle involvement including possible rhabdomyolysis and immune-mediated necrotizing myopathy.