Disease activity in pregnant women with multiple sclerosis who discontinued treatment

Takeaway

  • Disease reactivity 1 year postpartum was lower among women with multiple sclerosis (MS) who suspended rituximab (RTX) treatment before pregnancy, compared with women who suspended natalizumab (NTZ) treatment, suggesting that RTX may exert long-acting effects on MS disease activity.

Why this matters

    Pregnant women with MS are required to cease drug treatment, however, newer therapies such as RTX, which possess extended biological effects, may diminish the risk of disease reactivity if taken before conception.

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