Effectiveness of nucleus basalis of Meynert stimulation for Lewy body dementia: Phase 1 study


  • Nucleus basalis of Meynert deep brain stimulation (NBM-DBS) for Lewy body dementia (LBD) was well tolerated but resulted in decreased cognitive function, with no significant improvement in cognitive or behavioral status at 3 months, and increased brain occipital metabolic activity.

Why this matters

    Preliminary studies had indicated that NBM-DBS may be a new therapeutic option in patients with LBD, however more studies were needed to assess safety and potential therapeutic effects.

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