Is clobazam an effective and tolerable adjunctive therapy for adults with drug-resistant epilepsy?

Takeaway

  • Clobazam treatment was well-tolerated and effective as an adjunctive agent for adults with drug-resistant epilepsy across multiple epilepsy classifications.

Why this matters

    Following the approval of clobazam by the Federal Drug Administration in 2011, off-label use has increased and preliminary data suggest that clobazam may be an effective adjunctive therapy for adults with drug-resistant epilepsy. However, the efficacy and tolerability of clobazam for this indication is unknown.

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