Motor unit number index as a biomarker for disease severity in adult onset spinal muscular atrophy


  • Proximal weakness in the lower limbs was the most common symptom in people with spinal muscular atrophy (SMA) type 4, and motor unit number index (MUNIX) strongly correlated with duration of disease.

Why this matters ?

    The findings reiterate the concept of SMA as a spectrum that is not related to pediatric age, allowing for more effective initial diagnosis and earlier treatment.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.